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Peyronie's Disease

Last Updated 8/8/2010 1:46:40 PM


Peyronie’s disease (PD) is a fibrotic tissue disorder of the penis that is characterized by the presence of excess collagen formations (often called plaque) that affects the erectile bodies of the penis. The fibrotic lesions reduce penile tissue elasticity and can result in penile curvature, painful erections, constrictions (hour-glass deformity), loss of length or girth and erectile dysfunction. PD typically affects men that are 40 years of age and older.

Trauma to the penis is one of the most common causes of PD and can result during regular sexual intercourse when the penis bends or is struck severely, leading to scar tissue formation or plaques. These plaques can decrease normal tissue elasticity with the resultant changes in penile appearance.

Genetics can also play a role in predisposing an individual to PD. Individuals with this condition have a certain type of immune cell marker, which indicates the condition may be inherited. The presence of a family member with PD or other fibrotic tissue disorders such as Dupuytren’s contracture or plantar fibromatosis is associated with this condition.

Treatment Options

Treatment options for patients vary and depend on the degree of curvature and sexual disability in the individual patient. Treatment options may include:

  • Injections of medication into the fibrous band of tissue
  • Lithotripsy
  • Oral or topical medications
  • Radiation therapy
  • Surgery (Penile Plication or Mechanical Traction Devices)
  • Vitamin E

PD can often be a source of significant anxiety and concern. The specialists at the Men's Health Program are available to diagnosis and help treat patients with Peryonie's Disease.

Men's Health Program:
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