El Camino Heart & Vascular Institute Clinical Trials

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Heart & Vascular Institute Clinical Trials

Last Updated 8/18/2010 8:07:28 AM

The Heart & Vascular Institute conducts advanced clinical research comparable to academic medical centers. Our physicians are making a variety of clinical trials available to their patients, giving them access to new experimental therapies for conditions that may not respond adequately to existing approaches, as well as advancing the treatment technologies for the region.

For more detailed information and patient enrollment please call 650-962-4566.

Carotid Artery Disease

Clinical trial	Purpose
ACT I	To evaluate the equivalence of carotid artery stenting using the Abbott Vascular Xact^(R) stent and Emboshield^(R) embolic protection system when compared to endarterectomy in low-surgical-risk patients. This is a multicenter randomized study with three out of four patients receiving a stent.
Post-market studies	To evaluate the use of FDA-approved carotid stents and embolic protection systems in high-risk patients: CHOICE (Abbott), SAPPHIRE WW (Cordis), and CREATE PAS (ev3)

Electrophysiology

Clinical trial	Purpose
OPTIMISE CRT	A randomized study to evaluate the benefit of using the Quick Opt method compared to the standard method of programming a Cardiac Resynchronization Therapy Device (CRT-D) to improve mechanical indices, symptoms, and exercise.

Coronary Artery Disease

Clinical trial	Purpose
EDUCATE	The purpose of the study is to better understand the safety and efficacy of 12 months versus 30 months of dual antiplatelet therapy (DAPT) in patients that have received the Endeavor drug eluting stent for coronary artery stenosis. In addition, data will be collected to evaluate the relationship between DAPT compliance and therapy interruptions, and the resulting clinical events.

Lower Extremity Disease

Clinical trial	Purpose
DEFINITIVE LE	A non-randomized study to evaluate the intermediate and long-term effectiveness of the SilverHawk and TurboHawk peripheral plaque excision systems for the endovascular treatment of peripheral artery disease in the femoropopliteal and tibial-peroneal arteries
iCAST	A non-randomized study to evaluate the non-inferiority of the iCAST covered stent (Atrium Medical) for treating iliac artery stenosis in patients with de novo or restenotic lesions in the common and/or external iliac arteries.

Mitral Valve Regurgitation

Clinical trial	Purpose
EVEREST II (REALISM)	Continued access registry to provide additional information regarding the endovascular approach to treatment of mitral valve regurgitation using the Evalve Cardiovascular Valve Repair System (MitraClip) and to evaluate changes in functional capacity after successful MitraClip treatment.

Stroke

Clinical trial	Purpose
CRYSTAL AF	A randomized study to evaluate whether patients who have suffered a cryptogenic stroke, a stroke of unknown cause, may benefit from the timely detection of atrial fibrillation using the Reveal XT Insertable Cardiac Monitor device.

Clinical Trial Contact Information

If you would like information about enrolling into a clinical trial at the Heart and Vascular Institute at El Camino Hospital, please contact our Clinical Research Manager at :

El Camino Hospital - Mountain View
2490 Hospital Drive, Suite 310
Mountain View, CA 94040
650-962-4566

Video: Less Invasive Mitral Valve Regurgitation Repair

Chad Rammohan, MD, discusses mitral valve regurgitation, including traditional forms of treatment such as open-heart surgery, and a newer treatment called the Evalve procedure. The Evalve procedure uses an investigational device that is pending FDA approval; the procedure is available in an FDA-approved clinical trial at El Camino Hospital.